Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
IDP2
Systematic Name
YLR174W
Strain
S288c
Description
Cytosolic NADP-specific isocitrate dehydrogenase; catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose; IDP2 has a paralog, IDP3, that arose from the whole genome duplication; mutation in human homolog IDH1 is associated with low-grade gliomas and secondary glioblastomas
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>IDP2 YLR174W
ATGACAAAGATTAAGGTAGCTAACCCCATTGTGGAAATGGACGGCGATGAGCAAACAAGA
ATAATCTGGCATTTAATCAGGGACAAGTTAGTCTTGCCCTATCTTGACGTTGATTTGAAG
TACTACGATCTTTCCGTGGAGTATCGTGACCAGACTAATGATCAAGTAACTGTGGATTCT
GCCACCGCGACTTTAAAGTATGGAGTAGCTGTCAAATGCGCGACTATTACACCCGATGAG
GCAAGGGTCGAGGAATTTCATTTGAAAAAGATGTGGAAATCTCCAAATGGTACTATTAGA
AACATTTTGGGTGGTACAGTGTTCAGAGAACCTATTATTATCCCTAGAATTCCAAGGCTA
GTTCCTCAATGGGAGAAGCCCATCATCATTGGGAGACACGCATTCGGCGATCAGTACAAA
GCTACCGATGTAATAGTCCCTGAAGAAGGCGAGTTGAGGCTTGTTTATAAATCCAAGAGC
GGAACTCATGATGTAGATCTGAAGGTATTTGACTACCCAGAACATGGTGGGGTTGCCATG
ATGATGTACAACACTACAGATTCGATCGAAGGGTTTGCGAAGGCCTCCTTTGAATTGGCC
ATTGAAAGGAAGTTACCATTATATTCCACTACTAAGAATACTATTTTGAAGAAGTATGAT
GGTAAATTCAAAGATGTTTTCGAAGCCATGTATGCTAGAAGTTATAAAGAGAAGTTTGAA
TCCCTTGGCATCTGGTACGAGCACCGTTTAATTGATGATATGGTGGCCCAAATGTTGAAA
TCTAAAGGTGGATACATAATTGCCATGAAAAATTACGACGGTGACGTAGAATCAGATATT
GTTGCACAAGGATTTGGCTCCTTGGGGTTAATGACATCTGTGTTGATTACCCCGGACGGT
AAAACCTTTGAAAGCGAAGCCGCCCACGGTACAGTAACAAGACATTTTAGACAGCATCAG
CAAGGAAAGGAGACGTCAACAAATTCCATTGCATCAATTTTCGCGTGGACTAGAGGTATT
ATTCAAAGGGGTAAACTTGATAATACTCCAGATGTAGTTAAGTTCGGCCAAATATTGGAA
AGCGCTACGGTAAATACAGTGCAAGAAGATGGAATCATGACTAAAGATTTGGCGCTCATT
CTCGGTAAGTCTGAAAGATCCGCTTATGTCACTACCGAGGAGTTCATTGACGCGGTGGAA
TCTAGATTGAAAAAAGAGTTCGAGGCAGCTGCATTGTAA
Promoter Sequence
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>IDP2 YLR174W
AATAGTCTTACACCAATGAGCCAAATAGTGAATGCGGTCCTGAACCAGAACGAGACTGTT
ACGTTCGCAGCAAGAGGCCATGTCCTTGAAGATGGTATAGATAATAACTCATTGATTCCA
GCAGACATGCTGGAGGATATTTTCCAAGAAGCATCGTTTATTCCCATTACTACCAATGCT
ACGTTTAACTCCAGTGAATTGATTCAAGAGTTTCAGATCAACGATCTTCAGCTACGGTGG
GCAGCGCGCAAAAAGCTCAGTCTTGTGGGGACATTTTTAGGATTCTTTGATCTATCCTTC
TACGAGACGCACCAGCAAGACCGAGTTCGCATCGATACCATTCGGGGACAGATCGATCTG
TACCATAACGACATCAATTTCTTAAACTTACCCATGAAGCAATGGATCAACTCTTCATCG
CACATTCTGCACGATGAGGACACAGGAAATACGCAGATGAAGCTTCAATTTGATCTAGAA
AATGACGACATGGAAGTCGTCAATAGCTTGGAACTAACACGAACCCTGAACGAAATACTA
TTCCAGGGTTTTACAGTTATTCACTTTAATGCGACGATAGATGCGTCACTTACGACGGCA
TTGGGCCCGTGGGTTCTCACCGGGTTAGCCGGAGAGGGTGACACTTTGGTCACGTGAACG
TCTATCTATTTATTTTTATAACTCCGGGATGTCATTGCCGGTGGTCCGAAAATCGGCAAA
TAAGGAAATAAGGGAAGAATATGCAGTAGTCAAATCATCAGTGTTCTCTTTGATACCTTT
CAGGGCTAGGAATAGTGGGGGTGGAGTATAATATCAAAAACCGGACTTAACATTATTGGT
TCGGTTGGAATTGGCTATAGGCAAACTAGTCTCCGGCATGATATATAAATGACAGCCTGC
AATTGTATGTTACTACACTCTTGACTTGTCGACTACAGTCGCTGCTCAGGCACGAGAATA
GGAGGTAAGAAGGTAACGTACGTATATATATAAAATCGTA
Chr coordinates
Chr XII from 504591-505829