PathoYeastract
C.albicans
YEASTRACT+
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Modelling prediction
Essentiality
[metab] Optimisation
manipulating gene expression
manipulating TF expression
Cross species
Promoter analysis
Homologous network
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Regulatory Associations
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ORF List ⇔ Gene List
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TF-Consensus List
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Upstream Sequence
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Sir2p
Description
Verified ORF; (orf19.1992) Histone deacetylase, sirtuin, required for wild-type lifespan, asymmetric inheritance of oxidatively damaged proteins, rDNA silencing; regulates phenotypic switch in strain 3153A, not in WO-1
GO Terms:
Biological Process
level 5:
regulation of cell differentiation
level 6:
rDNA heterochromatin formation
level 7:
recombination within rDNA repeats
level 9:
negative regulation of DNA recombination at telomere
GO Terms:
Molecular Function
level 5:
NAD+ binding
GO Terms:
Cellular Component
level 5:
nucleus
External source
Open in CGD
