PathoYeastract
C.albicans
YEASTRACT+
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Modelling prediction
Essentiality
[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Ncb2p
Description
Verified ORF; (orf19.5825) Beta subunit of NC2, heterodimeric regulator of transcription; activates CDR1 transcription; possibly an essential gene, disruptants not obtained by UAU1 method; conditional mutants show decreased susceptibility to azoles
GO Terms:
Biological Process
level 5:
regulation of cellular response to drug
level 6:
positive regulation of transcription from RNA polymerase II promoter in response to heat stress
level 6:
regulation of transcription from RNA polymerase II promoter in response to stress
level 7:
regulation of RNA polymerase II transcription preinitiation complex assembly
level 9:
negative regulation of transcription by RNA polymerase II
level 9:
positive regulation of transcription by RNA polymerase II
level 9:
RNA polymerase II preinitiation complex assembly
level 9:
negative regulation of transcription by RNA polymerase III
GO Terms:
Molecular Function
level 3:
chromatin binding
level 4:
transcription coactivator activity
level 4:
transcription corepressor activity
level 5:
protein heterodimerization activity
level 6:
TBP-class protein binding
level 6:
sequence-specific DNA binding
GO Terms:
Cellular Component
level 5:
nucleus
level 5:
negative cofactor 2 complex
External source
Open in CGD