C.albicans - PathoYeastract

Gene Ontology Information

Protein Name	Top2p
Description	Verified ORF; (orf19.2873) DNA topoisomerase II; catalyzes ATP-dependent DNA relaxation and decatenation in vitro; Y842 predicted to be catalytic; functional homolog of S. cerevisiae Top2p; sensitive to amsacrine or doxorubicin; farnesol-upregulated in biofilm
GO Terms: Biological Process	level 3: filamentous growth level 4: reciprocal meiotic recombination level 5: chromatin organization level 5: mitotic DNA integrity checkpoint signaling level 5: mitotic chromosome condensation level 5: mitotic sister chromatid separation level 5: resolution of meiotic recombination intermediates level 5: cellular response to starvation level 5: filamentous growth of a population of unicellular organisms in response to starvation level 6: cellular response to neutral pH level 6: DNA topological change level 6: filamentous growth of a population of unicellular organisms in response to neutral pH level 7: chromatin remodeling at centromere level 7: DNA strand elongation involved in DNA replication level 8: regulation of mitotic recombination level 9: rRNA transcription level 10: replication fork progression beyond termination site
GO Terms: Molecular Function	level 4: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity level 5: DNA binding level 6: ATP binding
GO Terms: Cellular Component	level 3: DNA replication termination region level 4: synaptonemal complex level 4: chromosome, centromeric core domain level 5: nucleus
External source	Open in CGD