C.albicans - PathoYeastract

Gene Ontology Information

Protein Name	Pra1p
Description	Verified ORF; (orf19.3111) Cell surface protein that sequesters zinc from host tissue; enriched at hyphal tips; released extracellularly; binds to host complement regulators; mediates leukocyte adhesion and migration; immunogenic in mouse; produced at ambient pH
GO Terms: Biological Process	level 4: sequestering of zinc ion level 5: proteolysis level 5: adhesion of symbiont to host level 5: leukocyte cell-cell adhesion level 5: autophagy of mitochondrion level 6: piecemeal microautophagy of the nucleus level 7: evasion of host immune response level 7: negative regulation of complement activation level 8: modulation by symbiont of host cell-mediated immune response level 10: suppression by symbiont of host T-cell mediated immune response
GO Terms: Molecular Function	level 3: protein binding level 4: fibrinogen binding level 4: integrin binding level 5: metallopeptidase activity level 5: high molecular weight kininogen binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: extracellular region level 3: cell surface level 4: hyphal tip level 5: fungal-type cell wall level 6: hyphal cell wall
External source	Open in CGD