PathoYeastract
C.albicans
YEASTRACT+
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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Top1p
Description
Verified ORF; (orf19.96) DNA topoisomerase I; required for wild-type growth and for wild-type mouse virulence; sensitive to camptothecin; induced upon adherence to polystyrene; rat catheter biofilm induced
GO Terms:
Biological Process
level 2:
biological process involved in interspecies interaction between organisms
level 4:
hyphal growth
level 5:
chromatin organization
level 5:
mitotic chromosome condensation
level 5:
nuclear migration
level 6:
rDNA heterochromatin formation
level 6:
DNA topological change
level 7:
DNA strand elongation involved in DNA replication
level 8:
regulation of mitotic recombination
level 8:
regulation of transcription by RNA polymerase II
level 8:
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
level 8:
transcription elongation by RNA polymerase II promoter
level 9:
rRNA transcription
GO Terms:
Molecular Function
level 4:
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
level 5:
DNA binding
level 5:
DNA topoisomerase type I (single strand cut, ATP-independent) activity
GO Terms:
Cellular Component
level 3:
cytosol
level 4:
replication fork protection complex
level 5:
nucleus
level 5:
nucleolus
External source
Open in CGD