PathoYeastract
C.albicans
YEASTRACT+
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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Protein Name
Dfr1p
Description
Verified ORF; (orf19.5142) Trimethoprim resistant dihydrofolate reductase (DHFR), reduces 7,8-dihydrofolate to 5,4,7,8-tetrahydrofolate; binds NADPH; target of drugs that selectively inhibit the fungal enzyme rather than the human enzyme
GO Terms:
Biological Process
level 2:
metabolic process
level 6:
dihydrofolate metabolic process
level 7:
nucleotide biosynthetic process
level 7:
tetrahydrofolate biosynthetic process
level 8:
glycine biosynthetic process
GO Terms:
Molecular Function
level 5:
NADP binding
level 6:
dihydrofolate reductase activity
level 6:
mRNA binding
GO Terms:
Cellular Component
level 1:
cellular_component
External source
Open in CGD
