PubMed
Finkel JS et al., PLoS pathogens, 2012 Feb;8(2):e1002525Finkel JS et al., PLoS pathogens, 2012 Feb;8(2):e1002525
Indirect
Microarray analysis - WT vs TF Deletion
Positive
DAY185
Cell cycle/morphology
Grown from overnight YPD cultures and inoculated into 50 ml Spider medium at OD 0.2 for 8 hours at 37°C with 220-rpm agitation. Transcription factor gene deletion.
6.52188078
PubMed
Fanning S et al., Eukaryotic cell, 2012 Jul;11(7):896-904Fanning S et al., Eukaryotic cell, 2012 Jul;11(7):896-904
Indirect
Microarray analysis - WT vs TF Deletion
Positive
DAY185
Cell cycle/morphology
Cells were grown in Spider medium (1% nutrient broth, 1% d-mannitol, 0.2% K2HPO4). Transcription factor gene deletion.
6.703515
Indirect
Microarray analysis - WT vs TF Deletion
Positive
DAY185
Pathogenicity
Oropharyngeal candidiasis (OPC) mouse model was used. The mice were sacrificed after either 1 or 5 days of infection. Transcription factor gene deletion.
1.121793
PubMed
Huang MY et al., PLoS pathogens, 2019 May;15(5):e1007787Huang MY et al., PLoS pathogens, 2019 May;15(5):e1007787
Indirect
NanoString wt vs TF mutant
Positive
P57055
Cell cycle/morphology
Hyphal growth (RPMI + 10% serum at 37°C for 4 hours)