PathoYeastract
C.albicans
YEASTRACT+ INESC-ID IST IBB
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Regulation Reference(s)

The PathoYeastract team, is actively curating each regulation evidence code, association type and environmental condition.
Transcription
Factor		 Target
ORF/Genes		 References Evidence
Code		 Evidence
Experiment		 Association
Type		 Strain Environmental
Group		 Environmental
Condition		 Log2FC
Sef1p C2_02440W_A PubMed external link Xiong L et al., mSphere, 2024 Jul 30;9(7):e0037224Xiong L et al., mSphere, 2024 Jul 30;9(7):e0037224 Indirect RNA-seq analysis - WT vs TF Deletion Positive SC5314 Ion/metal/phosphate/sulfur/vitamin availability BPS: Cells were pre-cultured in liquid YPD (2% dextrose, 2% Bacto peptone, 1% yeast extract) rotating at 75 rpm at 30°C overnight. Cells were inoculated into 25 mL of pre-warmed (37°C) YPD + 500 µM BPS (bathophenanthrolinedisulfonate; iron chelator) at an initial OD600 of 0.2. Cultures were grown for 4 h with vigorous shaking (225 rpm) at 37°C, then harvested by vacuum filtration and immediately frozen at -80°C. 0.201109
PubMed external link Garg R et al., mSphere, 2025 Apr 29;10(4):e0004025Garg R et al., mSphere, 2025 Apr 29;10(4):e0004025 Indirect RNA-seq analysis - WT vs TF Deletion Positive SN250 Ion/metal/phosphate/sulfur/vitamin availability Fe-replete: Fe-depleted yeast nitrogen base (YNB) medium + 1.0 uM or 5 uM FeCl3 (as indicated per experiment); cells seeded at OD600 = 0.001; grown 48 h at 30 degrees C, 200 RPM (12-13 doublings). 0.301641
Indirect RNA-seq analysis - WT vs TF Deletion Positive SN250 Ion/metal/phosphate/sulfur/vitamin availability Fe-starvation: Fe-depleted yeast nitrogen base (YNB) medium; cells seeded at OD600 = 0.001; grown 48 h at 30 degrees C, 200 RPM (12-13 doublings). 0.57051