C.albicans - PathoYeastract

Regulation Reference(s)

The PathoYeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Sef1p	C3_03230C_A	PubMed Chen C et al., Cell host & microbe, 2011 Aug 18;10(2):118-35	Indirect	Microarray analysis - WT vs TF Deletion	Positive	SN250	Ion/metal/phosphate/sulfur/vitamin availability	Cells were inoculated into YPD (OD600=10⁻⁴), grown overnight, then diluted to OD600 0.01 in low iron media, incubated at 30°C for 5–6 hours, and harvested at OD600 0.5–0.6. Transcription factor gene deletion.	1.59314135
		PubMed Xiong L et al., mSphere, 2024 Jul 30;9(7):e0037224	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	SC5314	Ion/metal/phosphate/sulfur/vitamin availability	BPS: Cells were pre-cultured in liquid YPD (2% dextrose, 2% Bacto peptone, 1% yeast extract) rotating at 75 rpm at 30°C overnight. Cells were inoculated into 25 mL of pre-warmed (37°C) YPD + 500 µM BPS (bathophenanthrolinedisulfonate; iron chelator) at an initial OD600 of 0.2. Cultures were grown for 4 h with vigorous shaking (225 rpm) at 37°C, then harvested by vacuum filtration and immediately frozen at -80°C.	0.65457
		PubMed Garg R et al., mSphere, 2025 Apr 29;10(4):e0004025	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	SN250	Ion/metal/phosphate/sulfur/vitamin availability	Fe-starvation: Fe-depleted yeast nitrogen base (YNB) medium; cells seeded at OD600 = 0.001; grown 48 h at 30 degrees C, 200 RPM (12-13 doublings).	-0.729632