C.albicans - PathoYeastract

Regulation Reference(s)

The PathoYeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Sef1p	C6_02180W_A	PubMed Chen C et al., Cell host & microbe, 2011 Aug 18;10(2):118-35	Indirect	Microarray analysis - WT vs TF Deletion	Negative	SN250	Ion/metal/phosphate/sulfur/vitamin availability	Cells were inoculated into YPD (OD600=10⁻⁴), grown overnight, then diluted to OD600 0.01 in low iron media, incubated at 30°C for 5–6 hours, and harvested at OD600 0.5–0.6. Transcription factor gene deletion.	-0.8282674
		PubMed Junier A et al., mSphere, 2022 Feb 23;7(1):e0077921	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	pcz1	Ion/metal/phosphate/sulfur/vitamin availability	Grown overnight in a complete minimal medium minus uridine (CM-U) at 25°C. The cultures were treated with 4 μM of calcium ionophore A23187. After 30 min of treatment, cells were harvested and frozen in RNAlater. Transcription factor gene deletion.	-0.875842950555252
		PubMed Junier A et al., mSphere, 2022 Feb 23;7(1):e0077921	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	pcz1	Stress	Grown overnight in a complete minimal medium minus uridine (CM-U) at 25°C. The cultures were treated with a vehicle control (100% ethanol). After 30 min of treatment, cells were harvested and frozen in RNAlater.Transcription factor gene deletion.	-0.832835849244801
		PubMed Garg R et al., mSphere, 2025 Apr 29;10(4):e0004025	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	SN250	Ion/metal/phosphate/sulfur/vitamin availability	Fe-replete: Fe-depleted yeast nitrogen base (YNB) medium + 1.0 uM or 5 uM FeCl3 (as indicated per experiment); cells seeded at OD600 = 0.001; grown 48 h at 30 degrees C, 200 RPM (12-13 doublings).	-0.44127