S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Atg8p
Description	Component of autophagosomes and Cvt vesicles; regulator of Atg1p, targets it to autophagosomes; binds the Atg1p-Atg13p complex, triggering its vacuolar degradation; unique ubiquitin-like protein whose conjugation target is lipid phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation; deconjugation of Atg8p-PE is required for efficient autophagosome biogenesis
GO Terms: Biological Process	level 3: protein-containing complex localization level 3: cytoplasm to vacuole targeting by the Cvt pathway level 4: protein localization to phagophore assembly site level 4: endoplasmic reticulum to Golgi vesicle-mediated transport level 4: protein targeting to vacuole involved in autophagy level 4: autophagy of mitochondrion level 4: lipid droplet formation level 5: piecemeal microautophagy of the nucleus level 5: nucleophagy level 5: cellular response to nitrogen starvation level 5: membrane fusion level 5: reticulophagy level 5: autophagosome maturation level 5: mitophagy level 5: regulation of membrane invagination level 6: autophagosome assembly level 7: regulation of macroautophagy
GO Terms: Molecular Function	level 2: protein tag activity level 4: phosphatidylethanolamine binding
GO Terms: Cellular Component	level 2: cytosol level 2: phagophore assembly site level 3: vacuole-isolation membrane contact site level 4: lipid droplet level 4: mitochondrial membrane level 4: vacuolar membrane level 4: autophagosome level 5: autophagosome membrane level 5: Cvt vesicle membrane level 6: fungal-type vacuole membrane
External source	Open in SGD