S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Gdt1p
Description	Calcium and manganese transporter with higher affinity for Ca2+; involved in Ca2+ and Mn2+ homeostasis; localizes to the cis- and medial-Golgi apparatus; GFP-fusion localizes to the vacuole; required for the Mn2+-dependent function of glycosylation enzymes; TMEM165, a human ortholog linked to Congenital Disorders of Glycosylation, functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression regulated by Gcr1p
GO Terms: Biological Process	level 5: intracellular manganese ion homeostasis level 5: calcium ion transmembrane transport level 5: manganese ion transmembrane transport level 5: proton transmembrane transport level 5: intracellular calcium ion homeostasis level 6: Golgi calcium ion homeostasis level 7: calcium ion transport level 8: Golgi calcium ion transport
GO Terms: Molecular Function	level 5: metal ion transmembrane transporter activity level 6: manganese ion transmembrane transporter activity level 6: calcium ion transmembrane transporter activity
GO Terms: Cellular Component	level 3: Golgi apparatus level 4: cis-Golgi network level 5: fungal-type vacuole level 5: Golgi medial cisterna level 6: fungal-type vacuole membrane
External source	Open in SGD