S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rrp43p
Description	Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp43p (OIP2, EXOSC8); protein abundance increases in response to DNA replication stress
GO Terms: Biological Process	level 5: mRNA processing level 7: nuclear polyadenylation-dependent mRNA catabolic process level 7: rRNA catabolic process level 7: U1 snRNA 3'-end processing level 7: U4 snRNA 3'-end processing level 7: U5 snRNA 3'-end processing level 7: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 8: nuclear-transcribed mRNA catabolic process level 9: TRAMP-dependent tRNA surveillance pathway level 9: nuclear mRNA surveillance level 9: nuclear polyadenylation-dependent rRNA catabolic process
GO Terms: Molecular Function	level 0: molecular_function level 6: mRNA 3'-UTR AU-rich region binding
GO Terms: Cellular Component	level 2: nucleoplasm level 2: cytoplasm level 3: nuclear exosome (RNase complex) level 3: cytoplasmic exosome (RNase complex) level 4: nucleolus
External source	Open in SGD