S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Pat1p
Description	Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; binds to mRNAs under glucose starvation, most often in the 3' UTR; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress; phosphorylation by PKA inhibits P body foci formation
GO Terms: Biological Process	level 5: formation of translation preinitiation complex level 5: cellular response to glucose starvation level 7: P-body assembly level 7: deadenylation-dependent decapping of nuclear-transcribed mRNA level 8: regulation of translational initiation level 8: negative regulation of translation level 9: negative regulation of translational initiation
GO Terms: Molecular Function	level 2: protein-macromolecule adaptor activity level 2: chromatin binding level 2: protein binding level 3: RNA binding level 4: mRNA binding
GO Terms: Cellular Component	level 2: cytoplasm level 3: Lsm1-7-Pat1 complex level 3: kinetochore level 4: cytosolic small ribosomal subunit level 4: nucleus level 4: cytoplasmic stress granule level 4: P-body
External source	Open in SGD