Yeastract
YEASTRACT+ INESC-ID IST IBB
Home > Go Back > View Download     Tutorial     Help

 

Back to top top

Gene Ontology Information

Protein Name Npc2p
Description Sterol transport protein and functional homolog of human NPC2/He1; acts with Ncr1p in sterol trafficking; human NPC2 is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes; yeast NPC2 can complement mutations in human NPC2
GO Terms:
Biological Process		 level 5: microlipophagy external link
level 5: sterol transport external link
level 5: intracellular sterol transport external link
level 5: intermembrane sphingolipid transfer external link
GO Terms:
Molecular Function		 level 3: phosphatidylserine binding external link
level 3: sphingolipid transfer activity external link
level 4: phosphatidylcholine binding external link
level 4: sterol binding external link
level 5: phosphatidylinositol binding external link
GO Terms:
Cellular Component		 level 3: vacuole external link
level 5: fungal-type vacuole external link
level 5: fungal-type vacuole lumen external link
External source Open in SGD external link