S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Air2p
Description	RNA-binding subunit of the TRAMP nuclear RNA surveillance complex; involved in nuclear RNA processing and degradation; involved in TRAMP complex assembly as a bridge between Mtr4p and Trf4p; stimulates the poly(A) polymerase activity of Pap2p in vitro; has 5 zinc knuckle motifs; AIR2 has a paralog, AIR1, that arose from the whole genome duplication; Air2p and Air1p have nonredundant roles in regulation of substrate specificity of the exosome
GO Terms: Biological Process	level 6: tRNA modification level 6: polyadenylation-dependent RNA catabolic process level 8: nuclear polyadenylation-dependent snoRNA catabolic process level 8: nuclear polyadenylation-dependent snRNA catabolic process level 8: nuclear polyadenylation-dependent CUT catabolic process level 9: nuclear polyadenylation-dependent rRNA catabolic process level 9: TRAMP-dependent tRNA surveillance pathway level 10: nuclear mRNA surveillance of mRNA 3'-end processing
GO Terms: Molecular Function	level 2: nucleic acid binding level 2: protein-macromolecule adaptor activity level 3: RNA binding level 4: 3'-5' RNA helicase activity level 6: poly(A) RNA polymerase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: TRAMP complex level 4: nucleus level 4: nucleolus
External source	Open in SGD