S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ufd2p
Description	Ubiquitin (Ub) chain assembly factor (E4); forms branched Ub chains on substrates destined for degradation, catalyzing K48-linked multi-monoubiquitination of K29-linked Ub chains assembled by the Ub-ligase Ufd4p; involved in the Ub-fusion degradation pathway, OLE membrane fluidity pathway, stress response survival and the ERAD pathway for misfolded proteins, where it promotes ubiquitination and transfer of ERAD substrates to Rad23p; U-box family member; homologous to human Ufd2a and Ufd2b
GO Terms: Biological Process	level 3: ERAD pathway level 5: positive regulation of reciprocal meiotic recombination level 6: cellular response to ethanol level 7: ubiquitin-dependent protein catabolic process level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 9: protein ubiquitination level 11: positive regulation of protein ubiquitination level 11: protein K48-linked ubiquitination
GO Terms: Molecular Function	level 4: ubiquitin-protein transferase activity level 5: ubiquitin protein ligase activity level 6: ubiquitin-ubiquitin ligase activity
GO Terms: Cellular Component	level 2: cytoplasm level 3: ubiquitin ligase complex level 4: nucleus
External source	Open in SGD