Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Sac6p
Description Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant
GO Terms:
Biological Process		 level 4: actin filament organization external link
level 5: actin filament bundle assembly external link
level 5: actin filament network formation external link
level 6: formin-nucleated actin cable organization external link
level 7: formin-nucleated actin cable assembly external link
GO Terms:
Molecular Function		 level 2: protein-macromolecule adaptor activity external link
level 3: actin filament binding external link
GO Terms:
Cellular Component		 level 2: actin filament bundle external link
level 2: cytoplasm external link
level 3: actin cortical patch external link
level 3: mating projection tip external link
level 3: plasma membrane external link
level 3: cellular bud tip external link
level 6: actin filament external link
External source Open in SGD external link