S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ume6p
Description	Rpd3L histone deacetylase complex subunit; key transcriptional regulator of early meiotic genes; involved in chromatin remodeling and transcriptional repression via DNA looping; binds URS1 upstream regulatory sequence, represses transcription by recruiting conserved histone deacetylase Rpd3p (through co-repressor Sin3p) and chromatin-remodeling factor Isw2p; couples metabolic responses to nutritional cues with initiation and progression of meiosis
GO Terms: Biological Process	level 2: meiotic cell cycle level 3: spore germination level 3: mitotic cell cycle level 3: pseudohyphal growth level 5: lipid droplet organization level 5: chromatin remodeling level 5: cellular response to nitrogen starvation level 6: regulation of alcohol biosynthetic process level 8: regulation of DNA-templated transcription level 8: negative regulation of inositol biosynthetic process level 9: positive regulation of phosphatidylcholine biosynthetic process level 9: positive regulation of phosphatidylserine biosynthetic process level 10: negative regulation of transcription by RNA polymerase II level 10: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 3: DNA-binding transcription factor activity, RNA polymerase II-specific level 4: sequence-specific DNA binding level 4: DNA-binding transcription repressor activity, RNA polymerase II-specific level 4: DNA-binding transcription factor binding level 6: RNA polymerase II cis-regulatory region sequence-specific DNA binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: Rpd3L-Expanded complex level 4: Rpd3L complex level 4: nucleus
External source	Open in SGD