S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Gic2p
Description	Rho-family GTPase interacting protein and Cdc42p effector; required with Gic1p for cell polarity establishment and initiation of budding; involved in recruitment of septins to the presumptive bud site; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; gic1 gic2 double mutants are defective for polarizing Cdc42p at elevated temperature, so may function both up- and downstream of Cdc42p; regulates mitotic exit
GO Terms: Biological Process	level 3: establishment of cell polarity level 7: regulation of exit from mitosis level 7: septin ring organization level 7: Cdc42 protein signal transduction level 7: positive regulation of formin-nucleated actin cable assembly
GO Terms: Molecular Function	level 5: small GTPase binding level 5: phosphatidylinositol-4,5-bisphosphate binding
GO Terms: Cellular Component	level 3: cellular bud neck level 3: cell cortex level 3: incipient cellular bud site level 3: mating projection tip level 3: plasma membrane level 3: cellular bud tip level 4: cytoskeleton
External source	Open in SGD