S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dnf1p
Description	Aminophospholipid translocase (flippase); type 4 P-type ATPase; involved in phospholipid translocation, contributing to endocytosis, protein transport, and cellular polarization; localizes primarily to the plasma membrane; localizes to the shmoo tip where it has a redundant role in the cellular response to mating pheromone; DNF1 has a paralog, DNF2, that arose from the whole genome duplication
GO Terms: Biological Process	level 2: establishment or maintenance of cell polarity level 4: intracellular protein transport level 5: phospholipid transport level 5: phospholipid translocation level 5: endocytosis level 6: ceramide translocation level 6: aminophospholipid translocation
GO Terms: Molecular Function	level 2: ATPase-coupled intramembrane lipid carrier activity level 2: ATP hydrolysis activity level 3: nucleotide binding level 4: phosphatidylserine floppase activity level 4: ATP binding level 4: phosphatidylcholine flippase activity level 4: glycosylceramide flippase activity level 4: phosphatidylcholine floppase activity level 5: phosphatidylserine flippase activity level 5: phosphatidylethanolamine flippase activity level 6: magnesium ion binding
GO Terms: Cellular Component	level 2: membrane level 2: cell septum level 2: cellular bud level 2: cell periphery level 3: mitochondrion level 3: endoplasmic reticulum level 3: Golgi apparatus level 3: plasma membrane level 3: phospholipid-translocating ATPase complex level 3: cellular bud neck level 4: endosome membrane level 4: mating projection tip membrane
External source	Open in SGD