S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tif4632p
Description	Translation initiation factor eIF4G and scaffold protein; subunit of the mRNA cap-binding protein complex (eIF4F) with eIF4E (Cdc33p) and eIF4A (Tif1p/Tif2p); proposed to stimulate the ATPase and helicase activities of eIF4A synergistically with eIF4G based on sequence similarity with Tif4631p; proposed to be required with eIF4E for Ded1p-mediated stimulation of mRNA recruitment during 48S preinitiation complex (PIC) assembly; associated with Pab1p-mediated poly(A)-tail stimulated, translation
GO Terms: Biological Process	level 3: translational initiation level 5: cellular response to glucose starvation level 7: cytoplasmic stress granule assembly level 7: positive regulation of formation of translation preinitiation complex
GO Terms: Molecular Function	level 2: translation initiation factor activity level 2: protein binding level 3: translation initiation factor binding level 3: ATPase activator activity level 3: RNA binding level 4: mRNA binding
GO Terms: Cellular Component	level 2: cytoplasm level 3: eukaryotic translation initiation factor 4F complex level 4: cytoplasmic stress granule level 4: P-body
External source	Open in SGD