S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sgf73p
Description	Subunit of DUBm module of SAGA and SLIK; has roles in anchoring deubiquitination module (DUBm) into SAGA and SLIK complexes, maintaining organization and ubiquitin-binding conformation of Ubp8p, thereby contributing to overall DUBm activity; involved in preinitiation complex assembly at promoters; relocalizes to cytosol under hypoxia; human homolog ATXN7 implicated in spinocerebellar ataxia, and can complement yeast null mutant
GO Terms: Biological Process	level 4: chromatin organization level 5: chromatin remodeling level 5: regulation of protein localization to chromatin level 5: protein-containing complex assembly level 6: RITS complex assembly level 6: mRNA export from nucleus level 6: regulation of nucleocytoplasmic transport level 7: positive regulation of RNA polymerase II transcription preinitiation complex assembly level 9: regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 1: structural molecule activity level 3: enzyme activator activity level 4: histone acetyltransferase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 2: cytosol level 2: cytoplasm level 3: DUBm complex level 4: SAGA complex level 4: nucleus level 5: SLIK (SAGA-like) complex
External source	Open in SGD