S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Prp43p
Description	RNA helicase in the DEAH-box family; functions in both RNA polymerase I and polymerase II transcript metabolism; catalyzes removal of U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleoprotein complex; required for efficient biogenesis of both small- and large-subunit rRNAs; acts with Sqs1p to promote 20S to 18S rRNA processing catalyzed by endonuclease Nob1p
GO Terms: Biological Process	level 4: ribonucleoprotein complex biogenesis level 5: ribosomal large subunit biogenesis level 5: rRNA processing level 6: maturation of SSU-rRNA level 7: spliceosomal complex disassembly level 7: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 7: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 7: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO Terms: Molecular Function	level 2: nucleic acid binding level 2: ATP hydrolysis activity level 2: helicase activity level 2: ATP-dependent activity, acting on RNA level 3: RNA binding level 3: RNA helicase activity level 4: mRNA binding level 4: ATP binding
GO Terms: Cellular Component	level 3: spliceosomal complex level 3: mitochondrion level 4: 90S preribosome level 4: post-mRNA release spliceosomal complex level 4: nucleus
External source	Open in SGD