S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Hxk2p
Description	Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1
GO Terms: Biological Process	level 3: carbohydrate derivative metabolic process level 4: intracellular glucose homeostasis level 4: glycolytic process level 4: glucose 6-phosphate metabolic process level 4: carbohydrate metabolic process level 4: organophosphate metabolic process level 5: regulation of cell size level 5: hexose metabolic process level 6: glucose metabolic process level 6: mannose metabolic process level 6: D-glucose import across plasma membrane level 6: fructose import across plasma membrane level 6: negative regulation of apoptotic signaling pathway level 6: fructose metabolic process level 6: bifid shunt level 7: fructose catabolic process level 7: mannose catabolic process level 9: regulation of transcription by glucose
GO Terms: Molecular Function	level 4: ATP binding level 4: D-glucose binding level 5: glucokinase activity level 5: hexokinase activity level 6: fructokinase activity level 6: mannokinase activity
GO Terms: Cellular Component	level 2: cytosol level 3: mitochondrion level 4: mitochondrial membrane level 4: cytoplasmic side of mitochondrial outer membrane level 4: nucleus
External source	Open in SGD