Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Erv1p
Description Flavin-linked sulfhydryl oxidase of the mitochondrial IMS; N-terminus is an intrinsically disordered domain that in the cytosol helps target Erv1p to mitochondria, and in the intermembrane space oxidizes Mia40p as part of a disulfide relay system that promotes intermembrane space retention of imported proteins; functional ortholog of human GFER (ALR); human GFER carrying N-terminal 21 amino acids of Erv1p functionally complements the lethality of the erv1 null mutation
GO Terms:
Biological Process		 level 4: intracellular iron ion homeostasis external link
level 4: cellular response to oxidative stress external link
level 6: protein import into mitochondrial intermembrane space external link
level 7: protein import into the intermembrane space via the disulfide relay system external link
GO Terms:
Molecular Function		 level 4: flavin-dependent sulfhydryl oxidase activity external link
level 4: flavin adenine dinucleotide binding external link
level 5: thiol oxidase activity external link
GO Terms:
Cellular Component		 level 3: mitochondrion external link
level 4: mitochondrial intermembrane space external link
External source Open in SGD external link