S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dna2p
Description	Tripartite DNA replication factor; single-stranded DNA-dependent ATPase, ATP-dependent nuclease, helicase; tracking protein for flap cleavage during Okazaki fragment maturation; involved in DNA repair/processing of meiotic DNA double strand breaks; component of telomeric chromatin with cell-cycle dependent localization; required for telomerase-dependent telomere synthesis; forms nuclear foci upon DNA replication stress; human homolog DNA2 complements yeast dna2 mutant
GO Terms: Biological Process	level 3: meiotic DNA double-strand break processing level 4: mitotic DNA replication checkpoint signaling level 5: DNA repair level 6: telomere maintenance level 6: DNA double-strand break processing level 6: double-strand break repair level 7: DNA-templated DNA replication level 8: lagging strand elongation level 8: replication fork reversal
GO Terms: Molecular Function	level 2: helicase activity level 2: ATP hydrolysis activity level 3: RNA binding level 3: DNA helicase activity level 4: single-stranded DNA helicase activity level 4: single-stranded DNA endonuclease activity level 4: 5'-3' DNA helicase activity level 5: 5'-flap endonuclease activity level 5: DNA hairpin binding level 5: four-way junction DNA binding level 5: telomeric G-quadruplex DNA binding level 6: protein serine/threonine kinase activator activity
GO Terms: Cellular Component	level 2: cytoplasm level 3: site of double-strand break level 3: chromosome, telomeric region level 4: nucleus level 4: chromosome
External source	Open in SGD