Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Hyr1p
Description Glutathione peroxidase; functions as hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce redox signal to Yap1p transcription factor; glutathione peroxidase activity is neuroprotective in models of Huntington's disease; HYR1 has a paralog, GPX1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 3: response to oxidative stress external link
level 3: cellular oxidant detoxification external link
level 4: glutathione metabolic process external link
level 4: cellular response to oxidative stress external link
GO Terms:
Molecular Function		 level 2: peroxidase activity external link
level 3: phospholipid-hydroperoxide glutathione peroxidase activity external link
level 3: glutathione peroxidase activity external link
level 4: thioredoxin-dependent peroxiredoxin activity external link
GO Terms:
Cellular Component		 level 2: cytosol external link
level 2: cytoplasm external link
level 3: mitochondrion external link
level 4: mitochondrial intermembrane space external link
level 5: peroxisomal matrix external link
External source Open in SGD external link