S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rfa3p
Description	Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication, repair, recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress
GO Terms: Biological Process	level 3: establishment of protein localization level 3: reciprocal meiotic recombination level 5: DNA repair level 6: DNA topological change level 6: nucleotide-excision repair level 6: DNA recombination level 6: heteroduplex formation level 6: DNA replication level 7: telomere maintenance via recombination level 7: double-strand break repair via homologous recombination level 7: mitotic recombination level 7: telomere maintenance via telomere lengthening level 8: telomere maintenance via telomerase level 9: protein ubiquitination
GO Terms: Molecular Function	level 3: DNA binding level 4: sequence-specific DNA binding level 4: double-stranded DNA binding
GO Terms: Cellular Component	level 3: chromosome, telomeric region level 3: DNA replication factor A complex level 4: nucleus level 5: condensed nuclear chromosome level 5: nuclear lumen
External source	Open in SGD