S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Osh6p
Description	Oxysterol-binding phosphatidylserine transferase; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication
GO Terms: Biological Process	level 3: maintenance of cell polarity level 3: exocytosis level 4: sterol homeostasis level 5: sterol transport level 5: piecemeal microautophagy of the nucleus level 5: endocytosis level 6: intermembrane phospholipid transfer level 6: sterol metabolic process
GO Terms: Molecular Function	level 2: lipid binding level 3: phosphatidylserine binding level 3: sterol transfer activity level 4: phosphatidic acid binding level 4: phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity level 4: sterol binding level 5: phosphatidylinositol-4-phosphate binding level 5: phosphatidylinositol-5-phosphate binding level 5: phosphatidylinositol-3,5-bisphosphate binding level 6: phosphatidylinositol-3,4-bisphosphate binding
GO Terms: Cellular Component	level 2: membrane level 2: cytoplasm level 2: cytosol level 3: endoplasmic reticulum-plasma membrane contact site level 3: plasma membrane level 4: endoplasmic reticulum membrane level 4: cortical endoplasmic reticulum
External source	Open in SGD