Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Srl3p
Description Repressor of transcription at Start; binds to SBF (Swi4p-Swi6p) at SCB promoter elements in G1 to repress transcription; inhibitor of Start that retains Cdc28-Cln3 at the ER; acts with Ydj1p to promote release of the complex in a growth-mediated positive feedback loop to trigger Start; Srl3p is unstable and degraded by SCF-Grr1 after Cdc28p-dependent phosphorylation; contains a GTB (G1/S transcription factor binding) motif; binds SBF-regulated promoters in HU-treated cells; Cdc28p substrate
GO Terms:
Biological Process		 level 4: G1/S transition of mitotic cell cycle external link
level 9: regulation of transcription by RNA polymerase II external link
GO Terms:
Molecular Function		 level 2: transcription coregulator activity external link
level 6: RNA polymerase II cis-regulatory region sequence-specific DNA binding external link
GO Terms:
Cellular Component		 level 2: cytoplasm external link
level 4: nucleus external link
External source Open in SGD external link