S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rtt109p
Description	Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p
GO Terms: Biological Process	level 3: cellular response to stress level 4: chromatin organization level 4: DNA damage response level 7: maintenance of rDNA level 7: regulation of double-strand break repair via nonhomologous end joining level 7: regulation of gene expression level 8: replication-born double-strand break repair via sister chromatid exchange level 9: transposable element silencing level 9: regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 4: histone acetyltransferase activity level 5: protein-lysine-acetyltransferase activity level 5: histone H3 acetyltransferase activity level 6: histone H3K56 acetyltransferase activity
GO Terms: Cellular Component	level 4: nucleus
External source	Open in SGD