S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad5p
Description	DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, and error-prone translesion synthesis; required for UV and MMS-associated unequal sister chromatid exchange (SCE) but not for double-strand break associated unequal SCE; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; human homolog HLTF can complement yeast null mutant
GO Terms: Biological Process	level 4: free ubiquitin chain polymerization level 5: DNA repair level 5: DNA damage tolerance level 6: double-strand break repair level 6: error-free postreplication DNA repair level 7: error-free translesion synthesis level 7: error-prone translesion synthesis level 9: protein ubiquitination level 10: protein polyubiquitination
GO Terms: Molecular Function	level 2: ATP-dependent activity, acting on DNA level 2: nucleic acid binding level 2: ATP hydrolysis activity level 4: four-way junction helicase activity level 4: ATP binding level 4: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides level 5: four-way junction DNA binding level 5: ubiquitin protein ligase activity level 5: Y-form DNA binding level 5: metal ion binding level 7: zinc ion binding
GO Terms: Cellular Component	level 2: chromatin level 2: cytoplasm level 3: chromosome, telomeric region level 4: nucleus level 4: chromosome
External source	Open in SGD