S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tis11p
Description	mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication
GO Terms: Biological Process	level 4: intracellular iron ion homeostasis level 5: response to iron ion starvation level 7: electron transport coupled proton transport level 8: nuclear-transcribed mRNA catabolic process level 9: negative regulation of mitochondrial translation level 9: negative regulation of cytoplasmic translation
GO Terms: Molecular Function	level 2: translation repressor activity level 4: mRNA binding level 5: metal ion binding level 7: zinc ion binding
GO Terms: Cellular Component	level 2: cytoplasm level 3: mitochondrion level 4: P-body level 4: nucleus
External source	Open in SGD