Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Irc20p
Description E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent NHEJ pathway; controls 2-um plasmid copy number by regulating the levels of the Flp1p recombinase; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; null mutant displays increased levels of spontaneous Rad52p foci
GO Terms:
Biological Process		 level 5: DNA repair external link
level 7: double-strand break repair via nonhomologous end joining external link
level 8: double-strand break repair via synthesis-dependent strand annealing external link
level 9: protein ubiquitination external link
GO Terms:
Molecular Function		 level 2: ATP-dependent activity, acting on DNA external link
level 2: ATP hydrolysis activity external link
level 2: helicase activity external link
level 4: ubiquitin-protein transferase activity external link
level 4: ATP binding external link
level 5: ubiquitin protein ligase activity external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component		 level 3: mitochondrion external link
level 4: nucleus external link
External source Open in SGD external link