S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Bud6p
Description	Actin- and formin-interacting protein; nucleation-promoting factor (NPF) for Bni1p and Bnr1p during actin cable assembly and organization; enhances Bnr1p-mediated actin nucleation, alleviating Hof1p inhibition through competitive binding; interacts with Bni1p via a C-terminal triple helical coiled-coil domain; role in polarized cell growth; isolated as a bipolar budding mutant; localizes to the presumptive bud site, small bud tips, the bud neck and secretory vesicles; potential Cdc28p substrate
GO Terms: Biological Process	level 3: establishment of cell polarity level 3: budding cell apical bud growth level 3: pseudohyphal growth level 4: astral microtubule organization level 4: regulation of protein localization level 4: bipolar cellular bud site selection level 5: regulation of actin cytoskeleton organization level 5: actin nucleation level 5: actin filament bundle assembly level 5: cellular hyperosmotic response level 7: positive regulation of actin nucleation level 7: positive regulation of formin-nucleated actin cable assembly
GO Terms: Molecular Function	level 3: enzyme activator activity level 4: cytoskeletal regulatory protein binding level 4: actin binding
GO Terms: Cellular Component	level 2: cytoplasm level 2: polarisome level 3: prospore membrane level 3: spindle pole body level 3: mating projection tip level 3: cellular bud tip level 3: cellular bud neck level 3: cell tip level 3: incipient cellular bud site level 4: secretory vesicle
External source	Open in SGD