S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sec61p
Description	Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex is required for SRP-independent protein translocation into the ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER
GO Terms: Biological Process	level 3: ERAD pathway level 3: establishment of protein localization level 4: protein transport level 4: retrograde protein transport, ER to cytosol level 5: misfolded protein transport level 5: SRP-dependent cotranslational protein targeting to membrane, translocation level 5: post-translational protein targeting to membrane, translocation
GO Terms: Molecular Function	level 1: signal sequence receptor activity level 3: peptide transmembrane transporter activity level 3: transmembrane protein transporter activity level 4: ribosome binding
GO Terms: Cellular Component	level 2: membrane level 3: endoplasmic reticulum level 4: endoplasmic reticulum membrane level 4: Sec61 translocon complex
External source	Open in SGD