S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ski2p
Description	Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome
GO Terms: Biological Process	level 6: RNA catabolic process level 7: mRNA catabolic process level 8: nuclear-transcribed mRNA catabolic process level 9: nuclear-transcribed mRNA catabolic process, non-stop decay level 10: nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
GO Terms: Molecular Function	level 2: ATP hydrolysis activity level 2: nucleic acid binding level 3: RNA binding level 3: RNA helicase activity level 4: mRNA binding level 4: ATP binding
GO Terms: Cellular Component	level 1: protein-containing complex level 2: Ski complex level 2: cytoplasm
External source	Open in SGD