S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sei1p
Description	Seipin involved in lipid droplet (LD) assembly; controls lipid particle morphology, number, and size; promotes initiation of LD formation on the ER; ensures that LDs bud from the ER towards the cytosolic side of the membrane; forms a complex with Ldb16p at ER-LD contact sites, stabilizing these sites; null mutants have localized accumulation of phosphatidic acid (PA) marker proteins; BSCL2, human homolog implicated in congenital lipodystrophy, complements yeast null mutant
GO Terms: Biological Process	level 3: intracellular protein localization level 4: acylglycerol homeostasis level 4: phospholipid homeostasis level 4: lipid droplet formation level 5: lipid droplet organization level 6: negative regulation of sphingolipid biosynthetic process level 7: positive regulation of lipid biosynthetic process
GO Terms: Molecular Function	level 4: protein homodimerization activity
GO Terms: Cellular Component	level 3: endoplasmic reticulum level 4: endoplasmic reticulum membrane level 4: cortical endoplasmic reticulum
External source	Open in SGD