Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Tcb2p
Description ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; contains 3 calcium and lipid binding domains; mRNA is targeted to bud; TCB2 has a paralog, TCB1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 4: phospholipid homeostasis external link
level 5: maintenance of protein localization in endoplasmic reticulum external link
level 5: ER to Golgi ceramide transport external link
level 5: endoplasmic reticulum membrane organization external link
level 6: regulation of phosphatidylinositol dephosphorylation external link
GO Terms:
Molecular Function		 level 2: lipid binding external link
GO Terms:
Cellular Component		 level 2: cellular bud external link
level 2: cell periphery external link
level 3: endoplasmic reticulum external link
level 3: plasma membrane external link
level 4: cortical endoplasmic reticulum external link
level 4: endoplasmic reticulum membrane external link
External source Open in SGD external link