Yeastract
YEASTRACT+ INESC-ID IST IBB
Home > Go Back > View Contact/Credits     Tutorial     Help

 

Back to top top

Gene Ontology Information

Protein Name Srv2p
Description CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog
GO Terms:
Biological Process		 level 3: actin filament severing external link
level 4: actin filament organization external link
level 5: positive regulation of mitochondrial fission external link
level 5: cytoskeleton organization external link
level 6: Ras protein signal transduction external link
level 6: actin filament depolymerization external link
level 7: positive regulation of actin filament depolymerization external link
level 7: regulation of actin filament polymerization external link
GO Terms:
Molecular Function		 level 4: actin binding external link
level 4: adenylate cyclase binding external link
GO Terms:
Cellular Component		 level 2: cytoplasm external link
level 3: mating projection tip external link
level 3: actin cortical patch external link
External source Open in SGD external link