S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Csl4p
Description	Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain an S1 RNA binding domain; human homolog EXOSC1 partially complements yeast csl4 null mutant, and can complement inviability of strain in which expression of CSL4 is repressed
GO Terms: Biological Process	level 4: RNA processing level 5: mRNA processing level 7: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 8: nuclear-transcribed mRNA catabolic process level 9: nuclear polyadenylation-dependent rRNA catabolic process level 9: TRAMP-dependent tRNA surveillance pathway level 9: nuclear-transcribed mRNA catabolic process, non-stop decay
GO Terms: Molecular Function	level 0: molecular_function level 3: RNA binding
GO Terms: Cellular Component	level 2: cytoplasm level 3: nuclear exosome (RNase complex) level 3: cytoplasmic exosome (RNase complex) level 3: exosome (RNase complex) level 4: nucleus level 4: nucleolus
External source	Open in SGD