S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ssk2p
Description	MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: regulation of actin cytoskeleton organization level 5: stress-activated MAPK cascade level 5: cellular hyperosmotic response level 5: osmosensory signaling via phosphorelay pathway level 6: p38MAPK cascade
GO Terms: Molecular Function	level 3: protein kinase activity level 4: actin binding level 4: ATP binding level 4: protein serine kinase activity level 5: MAP kinase kinase kinase activity
GO Terms: Cellular Component	level 2: cytoplasm level 2: cytosol level 3: incipient cellular bud site level 3: cellular bud tip level 3: cellular bud neck level 3: cell cortex
External source	Open in SGD