S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Aif1p
Description	Mitochondrial cell death effector; translocates to the nucleus in response to apoptotic stimuli; triggers apoptosis in cells lacking HXK2; homolog of mammalian Apoptosis-Inducing Factor, putative reductase
GO Terms: Biological Process	level 4: regulation of programmed cell death level 5: apoptotic mitochondrial changes level 5: respiratory electron transport chain level 5: response to singlet oxygen level 6: positive regulation of apoptotic process level 6: negative regulation of ferroptosis
GO Terms: Molecular Function	level 2: oxidoreductase activity level 2: electron-transferring-flavoprotein dehydrogenase activity level 4: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor level 4: flavin adenine dinucleotide binding
GO Terms: Cellular Component	level 2: cytoplasm level 3: mitochondrion level 4: mitochondrial membrane level 4: nucleus level 4: mitochondrial outer membrane
External source	Open in SGD