S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Pap2p
Description	Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia
GO Terms: Biological Process	level 4: meiotic DNA double-strand break formation level 5: RNA 3'-end processing level 6: polyadenylation-dependent mRNA catabolic process level 6: base-excision repair level 6: tRNA modification level 7: nuclear polyadenylation-dependent mRNA catabolic process level 7: polyadenylation-dependent ncRNA catabolic process level 7: poly(A)-dependent snoRNA 3'-end processing level 7: U4 snRNA 3'-end processing level 8: nuclear polyadenylation-dependent antisense transcript catabolic process level 8: histone mRNA catabolic process level 8: negative regulation of DNA recombination level 8: nuclear polyadenylation-dependent snoRNA catabolic process level 8: nuclear polyadenylation-dependent snRNA catabolic process level 8: nuclear polyadenylation-dependent CUT catabolic process level 9: nuclear polyadenylation-dependent rRNA catabolic process level 9: TRAMP-dependent tRNA surveillance pathway level 10: nuclear mRNA surveillance of mRNA 3'-end processing
GO Terms: Molecular Function	level 2: protein binding level 4: mRNA binding level 4: 5'-deoxyribose-5-phosphate lyase activity level 4: 3'-5' RNA helicase activity level 6: poly(A) RNA polymerase activity
GO Terms: Cellular Component	level 2: cytosol level 3: TRAMP complex level 4: nucleus level 4: nucleolus
External source	Open in SGD