S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rrp6p
Description	Nuclear exosome exonuclease component; has 3'-5' exonuclease activity that is regulated by Lrp1p; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; role in sn/snoRNAs precursor degradation; forms a stable heterodimer with Lrp1p; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based
GO Terms: Biological Process	level 4: RNA processing level 7: regulation of telomere maintenance level 7: U1 snRNA 3'-end processing level 7: nuclear polyadenylation-dependent mRNA catabolic process level 7: exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 7: U4 snRNA 3'-end processing level 7: post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery level 7: U5 snRNA 3'-end processing level 7: poly(A)-dependent snoRNA 3'-end processing level 8: nuclear polyadenylation-dependent CUT catabolic process level 8: nuclear polyadenylation-dependent antisense transcript catabolic process level 8: histone mRNA catabolic process level 8: nuclear polyadenylation-dependent snoRNA catabolic process level 8: nuclear polyadenylation-dependent snRNA catabolic process level 9: TRAMP-dependent tRNA surveillance pathway level 9: nuclear mRNA surveillance level 9: nuclear polyadenylation-dependent rRNA catabolic process
GO Terms: Molecular Function	level 2: nucleic acid binding level 3: nucleotide binding level 4: single-stranded RNA binding level 5: 3'-5' exonuclease activity level 5: rRNA primary transcript binding level 6: 3'-5'-RNA exonuclease activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: nuclear exosome (RNase complex) level 4: nucleus level 4: nucleolus
External source	Open in SGD