S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rat1p
Description	Nuclear 5' to 3' single-stranded RNA exonuclease; involved in RNA metabolism, including rRNA and snoRNA processing, as well as poly (A+) dependent and independent mRNA transcription termination; required for cotranscriptional pre-rRNA cleavage; displaces Cdk1p from elongating transcripts, especially as RNAPII reaches the poly(A) site, negatively regulates phosphorylation of the CTD of RNAPII, and inhibits RNAPII transcriptional elongation
GO Terms: Biological Process	level 5: sno(s)RNA processing level 5: rRNA processing level 6: mRNA splicing, via spliceosome level 7: NAD-cap decapping level 7: cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 8: nuclear-transcribed mRNA catabolic process level 9: nuclear mRNA surveillance level 9: nuclear polyadenylation-dependent rRNA catabolic process level 9: termination of RNA polymerase II transcription, poly(A)-coupled level 9: termination of RNA polymerase II transcription, exosome-dependent level 11: negative regulation of transcription elongation by RNA polymerase II
GO Terms: Molecular Function	level 2: nucleic acid binding level 3: RNA binding level 4: mRNA binding level 4: exonuclease activity level 6: 5'-3' RNA exonuclease activity
GO Terms: Cellular Component	level 3: mitochondrion level 4: nucleus
External source	Open in SGD