Yeastract
YEASTRACT+ INESC-ID IST IBB
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Gene Ontology Information

Protein Name Isu2p
Description Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant
GO Terms:
Biological Process		 level 4: intracellular iron ion homeostasis external link
level 6: iron-sulfur cluster assembly external link
level 8: tRNA wobble uridine modification external link
GO Terms:
Molecular Function		 level 0: molecular_function external link
level 4: iron-sulfur cluster binding external link
level 5: 2 iron, 2 sulfur cluster binding external link
level 7: iron ion binding external link
level 8: ferrous iron binding external link
GO Terms:
Cellular Component		 level 2: cytoplasm external link
level 4: mitochondrial matrix external link
External source Open in SGD external link