S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ldb19p
Description	Alpha-arrestin, Ub-ligase adaptor for Rsp5p; regulates starvation- and substrate-induced Ub-dependent endocytosis of select plasma membrane localized amino acid transporters, recruiting Rsp5p to its targets; role in basal internalization and turnover of Ste2p, mating and zygote formation; recruits Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, affecting cytosol and plasma membrane translocation; localization regulated by Rsp5p-dependent ubiquitination
GO Terms: Biological Process	level 3: cellular response to stress level 5: ubiquitin-dependent endocytosis level 5: cellular response to amino acid stimulus level 7: positive regulation of receptor internalization
GO Terms: Molecular Function	level 2: protein-macromolecule adaptor activity level 5: ubiquitin protein ligase binding
GO Terms: Cellular Component	level 2: cytoplasm level 2: cytosol level 3: Golgi apparatus level 3: plasma membrane level 5: Golgi trans cisterna
External source	Open in SGD